11 Best Everyday Vitamins For Women Over 40

Are you navigating the changes that come with turning 40? Your body has different nutritional needs now compared to your 20s and 30s. Women over 40 experience hormonal shifts, decreased metabolism, and changes in bone density that require specific nutritional support.

The right vitamins and supplements can make a significant difference in how you feel daily. Many women report increased energy, better sleep, improved skin elasticity, and stronger bones when they find the perfect supplement routine for their needs.

This guide explores the 11 best vitamins and supplements specifically formulated for women over 40. We focus on high-quality products available on Amazon that deliver results based on scientific research and customer experiences.

Key Takeaways

• Hormonal Changes Matter: Women over 40 experience significant hormonal shifts that affect everything from mood to bone health. Specific vitamins can help balance these changes and reduce symptoms.
• Quality Over Quantity: Not all supplements are created equal. Look for brands that use high-quality ingredients, proper dosages, and have third-party testing.
• Bioavailability Makes a Difference: How your body absorbs nutrients is crucial. Forms like vitamin D3 are better absorbed than D2, and chelated minerals typically have higher absorption rates than other forms.
• Bone Health Becomes Critical: After 40, women begin losing bone density more rapidly. Calcium, vitamin D, and magnesium work together to maintain strong bones and prevent osteoporosis.
• Energy Production Needs Support: Many women over 40 report fatigue and decreased energy. B vitamins, CoQ10, and iron can help support cellular energy production.
• Gut Health Affects Everything: Proper digestion and nutrient absorption become more important as we age. Probiotics can support better gut health and improve immune function.
• Brain Function Protection: Cognitive support becomes important as we age. Omega-3 fatty acids and B vitamins help maintain brain function and mental clarity.
• Heart Health Is Priority: Cardiovascular disease risk increases after menopause. Omega-3s, CoQ10, and magnesium support heart health.
• Skin Changes Can Be Addressed: Collagen production decreases with age, affecting skin elasticity. Collagen supplements, vitamin C, and biotin can help maintain skin health.
• Always Consult Healthcare Providers: Before starting any supplement regimen, speak with your doctor, especially if you have existing health conditions or take medications.
• Consistency Is Key: The benefits of vitamins and supplements are cumulative. Daily consistency delivers the best results over time.

New Chapter Every Woman’s One Daily 40+

New Chapter delivers one of the most comprehensive multivitamins specifically formulated for women over 40. This whole-food fermented supplement uses probiotics to enhance absorption and digestibility.

Features:

• Fermented with beneficial probiotics and whole foods
• Contains organic herbs including turmeric, red clover, and broccoli sprouts
• Non-GMO Project Verified and made with organic vegetables and herbs
• Provides targeted support for immune health, heart health, and stress management

Pros:

• Can be taken on an empty stomach without digestive discomfort
• Contains specific herbs for perimenopause support
• Provides balanced nutrients in forms your body can actually use
• Includes methylated B vitamins for better absorption

Cons:

• Higher price point than some competitors
• Capsules are on the larger side
• Some users report a strong herbal smell

New Chapter stands out because it prioritizes quality over quantity. Rather than mega-dosing on synthetic vitamins, it provides nutrients in their most bioavailable forms. The fermentation process creates a supplement that your body recognizes as food, not isolated chemicals.

The addition of organic herbs like maca, chaste tree, and schizandra berry makes this an excellent choice for women experiencing perimenopause symptoms. These botanicals have been used traditionally to help balance hormones and reduce common symptoms like hot flashes and mood swings.

MegaFood Women’s 40+ One Daily Multivitamin

MegaFood creates supplements using real foods as their foundation. Their Women’s 40+ formula supports the unique nutritional needs of women in this life stage.

Features:

• Contains 21 essential vitamins and minerals including B vitamins for energy
• Made with farm-fresh foods and added nutrients
• Certified glyphosate residue free and tested for 125+ herbicides and pesticides
• Includes organic herbs like nettle leaf and dandelion root

Pros:

• Made with real foods for better absorption and utilization
• Supports energy production, immune function, and bone health
• Contains methylated forms of B vitamins
• Can be taken on an empty stomach

Cons:

• Some users report an unpleasant taste and smell
• Tablet size is larger than some competitors
• More expensive than synthetic multivitamins

MegaFood uses a unique process where they pair essential nutrients with whole foods. This creates a supplement that delivers nutrients in forms your body recognizes and can use efficiently. The addition of organic herbs specifically chosen for women over 40 helps address common concerns like hormonal changes and decreased energy.

The methylated B vitamins in this formula are particularly important as many women have genetic variations that make it difficult to convert standard B vitamins into their active forms. By providing pre-activated B vitamins, MegaFood ensures you get the full benefit regardless of your genetic makeup.

Nature Made Vitamin D3 5000 IU

Vitamin D deficiency becomes increasingly common in women over 40, and this high-potency supplement helps address that critical need.

Features:

• Provides 5000 IU (125 mcg) of vitamin D3 per softgel
• Contains the more bioavailable D3 form rather than D2
• USP verified for purity and potency
• Oil-based softgel for better absorption

Pros:

• Highly absorbable form of vitamin D
• Helps support calcium absorption and bone health
• Supports immune function
• Small, easy-to-swallow softgel

Cons:

• Higher dose requires monitoring vitamin D levels
• Not suitable for vegetarians/vegans (D3 from lanolin)
• Contains soybean oil as a carrier

Vitamin D deficiency affects approximately 40% of women over 40, with even higher rates in those with darker skin tones or limited sun exposure. This supplement provides a therapeutic dose to help correct deficiencies and maintain optimal levels.

The D3 form used in this supplement is the same form your skin produces when exposed to sunlight, making it more effective at raising blood levels than the D2 form found in many cheaper supplements. Proper vitamin D levels are crucial for calcium absorption, immune function, mood regulation, and even hormone balance.

Pure Encapsulations Magnesium Glycinate

Magnesium is a critical mineral that becomes increasingly important as women age, and this highly absorbable form helps prevent common deficiencies.

Features:

• Contains 120 mg of elemental magnesium per capsule
• Uses the highly bioavailable glycinate form
• Free from common allergens and additives
• Independently tested for purity and potency

Pros:

• Gentle on the digestive system
• Helps with muscle relaxation and sleep quality
• Supports bone health when paired with calcium and vitamin D
• Can help reduce anxiety and stress

Cons:

• More expensive than other magnesium forms
• Requires multiple capsules for therapeutic dosing
• Some users report headaches as a side effect

Magnesium is involved in over 300 biochemical reactions in the body, yet up to 75% of Americans don’t get enough from their diet. This deficiency becomes even more common in women over 40.

The glycinate form used in this supplement binds magnesium to the amino acid glycine, creating a compound that is much gentler on the digestive system than other forms like oxide or citrate. This means you can take enough to address deficiency symptoms without causing digestive discomfort. Many users report improved sleep quality, reduced muscle cramps, and better stress management when supplementing with magnesium glycinate.

Nordic Naturals Omega Woman

This specialized omega-3 supplement is formulated specifically for the needs of women, with added evening primrose oil for hormonal support.

Features:

• Provides 500 mg of omega-3 fatty acids per serving
• Includes 800 mg of evening primrose oil
• Third-party tested for purity and freshness
• Lemon-flavored to minimize fishy taste and burping

Pros:

• Supports hormone balance and skin health
• Helps reduce inflammation throughout the body
• Supports heart and brain health
• Superior triglyceride form for better absorption

Cons:

• Higher price point than basic fish oil supplements
• Larger softgels can be difficult to swallow for some
• Requires refrigeration after opening

Omega-3 fatty acids become increasingly important for women over 40 as they help combat the rising inflammation that occurs with age. This formula combines high-quality fish oil with evening primrose oil, which contains gamma-linolenic acid (GLA) that can help balance hormones and reduce symptoms associated with perimenopause.

Nordic Naturals is known for their rigorous testing protocols and commitment to sustainability. Their oils are purified using oxygen-free processing to prevent oxidation and maintain freshness. The triglyceride form used in this supplement matches the natural form found in fish, making it more bioavailable than the ethyl ester form found in many cheaper supplements.

Garden of Life Dr. Formulated Probiotics for Women

This specialized probiotic blend supports digestive, vaginal, and immune health with strains specifically selected for women over 40.

Features:

• Contains 50 billion CFU from 16 probiotic strains
• Includes L. reuteri and L. fermentum for vaginal health
• Shelf-stable formula (no refrigeration needed)
• Contains organic prebiotic fiber to feed good bacteria

Pros:

• Targeted support for women’s specific health concerns
• High potency formula with diverse strains
• Delayed-release capsules protect probiotics from stomach acid
• Third-party tested for purity and potency

Cons:

• Premium price point
• Some users report increased gas initially
• Capsules are on the larger side

Gut health becomes increasingly important as we age, with research showing connections between gut bacteria and everything from immune function to hormone metabolism. This formula contains strains specifically selected to address the unique microbiome needs of women over 40.

The inclusion of L. reuteri and L. fermentum is particularly important for maintaining vaginal health, which can change during perimenopause due to hormonal fluctuations. The high colony count ensures that enough beneficial bacteria reach the intestines, even after some are inevitably lost during digestion.

Qunol Ultra CoQ10 100mg

This water-soluble form of CoQ10 provides critical support for cellular energy production, which naturally declines after 40.

Features:

• 100mg of water-soluble CoQ10 per softgel
• 3x better absorption than standard CoQ10 supplements
• Supports heart health and energy production
• Made in a GMP-certified facility

Pros:

• Superior absorption compared to standard CoQ10
• Supports energy production at the cellular level
• Beneficial for those taking statins
• Small, easy-to-swallow softgels

Cons:

• Higher cost than standard CoQ10 supplements
• Contains some synthetic additives
• Some users report digestive discomfort

CoQ10 production naturally declines with age, with levels at age 40 approximately 30% lower than at age 20. This decline affects energy production in every cell of your body, particularly in high-energy organs like the heart and brain.

Qunol’s water-soluble formula addresses the main limitation of standard CoQ10 supplements – poor absorption. By making the CoQ10 molecule water-soluble, this supplement achieves much higher bioavailability, ensuring that the CoQ10 actually reaches your cells where it’s needed. Many users report increased energy, better exercise tolerance, and improved cognitive function when supplementing with this high-absorption CoQ10.

MegaFood Blood Builder Iron Supplement

No products found.

This whole-food based iron supplement helps address the increased risk of iron deficiency that women face, particularly during perimenopause when menstrual cycles can become heavier.

Features:

• Contains 26mg of iron per tablet
• Includes vitamin C, folate, and B12 for better absorption and utilization
• Made with real food like beets and oranges
• Clinically proven to increase iron levels without side effects

Pros:

• Gentle on the stomach – can be taken on an empty stomach
• Does not cause constipation like many iron supplements
• Includes nutrients that enhance iron absorption
• Non-GMO, gluten-free, and tested for 125+ pesticides

Cons:

• More expensive than synthetic iron supplements
• Tablets are relatively large
• Some users report an earthy taste

Iron deficiency becomes more common in women over 40, particularly during perimenopause when menstrual cycles can become heavier or more erratic. This supplement addresses that need with a form of iron that’s easy to absorb and gentle on the digestive system.

What makes Blood Builder unique is the inclusion of whole foods like organic beets, which naturally contain compounds that help enhance iron absorption and utilization. The addition of vitamin C further increases iron absorption, while B12 and folate work with iron to support healthy red blood cell production.

Doctor’s Best Collagen Types 1 & 3 with Vitamin C

No products found.

This collagen supplement helps support the structure of skin, hair, nails, and joints – all areas that show visible changes after 40.

Features:

• Provides 6000mg of Types 1 & 3 collagen per serving
• Includes vitamin C for enhanced collagen synthesis
• Hydrolyzed for better absorption
• Sourced from pasture-raised, grass-fed cattle

Pros:

• Supports skin elasticity and moisture
• Helps strengthen hair and nails
• Supports joint comfort and flexibility
• Unflavored powder dissolves easily in beverages

Cons:

• Not suitable for vegetarians/vegans
• Some users report a slight taste when mixed with water
• Results take several weeks to become noticeable

Collagen production declines approximately 1% per year after age 20, with a dramatic acceleration around menopause. This decline affects skin elasticity, hair thickness, nail strength, and joint comfort – all common concerns for women over 40.

This supplement provides types 1 and 3 collagen, which make up about 90% of the collagen in your body and are critical for skin, hair, nails, and connective tissue. The hydrolyzation process breaks the collagen down into smaller peptides that are more easily absorbed and utilized by your body. Many users report improved skin moisture, reduced fine lines, stronger nails, and less joint discomfort after 4-8 weeks of consistent use.

Viva Naturals Organic Turmeric Curcumin with BioPerine

This high-potency turmeric supplement helps address the increased inflammation that occurs with age, supporting joint comfort and overall wellness.

Features:

• Contains 1950mg of organic turmeric per serving
• Includes 15mg of 95% standardized curcuminoids
• Contains BioPerine (black pepper extract) for enhanced absorption
• Organic, non-GMO, and vegetarian

Pros:

• Supports healthy inflammatory response
• Helps with joint comfort and mobility
• Provides antioxidant support
• Enhanced absorption formula

Cons:

• Large capsule size
• Some users report digestive upset
• Yellow staining possible if capsule breaks

Chronic, low-grade inflammation increases with age and contributes to many common concerns like joint discomfort, skin aging, and cardiovascular issues. Turmeric contains curcuminoids that help modulate this inflammation through multiple pathways.

The addition of BioPerine in this formula dramatically increases curcumin absorption – by up to 2000% in some studies. This ensures you get the maximum benefit from each dose. Many users report improved joint comfort, reduced stiffness, and better mobility after several weeks of consistent use.

Nature’s Bounty Biotin 5000mcg

This high-potency biotin supplement supports the health of hair, skin, and nails – all areas that commonly show changes after 40.

Features:

• Provides 5000mcg of biotin per softgel
• Rapid release softgel for better absorption
• USP verified for purity and potency
• Supports hair, skin, and nail health

Pros:

• Supports keratin production for stronger hair and nails
• May help reduce hair shedding
• Small, easy-to-swallow softgel
• Excellent value for the price

Cons:

• Can interfere with certain lab tests
• Some users report skin breakouts
• May take 3+ months to see results

Biotin plays a critical role in keratin production – the protein that forms the structure of hair, skin, and nails. Many women notice changes in these areas after 40, with hair becoming thinner, nails more brittle, and skin less elastic.

This supplement provides a therapeutic dose of biotin to support these structures from within. Many users report stronger nails, reduced hair shedding, and improved skin texture after 2-3 months of consistent use. The softgel delivery system helps enhance absorption compared to tablet forms.

FAQs

How do vitamin needs change for women over 40?

Women over 40 need increased amounts of certain nutrients like vitamin D, calcium, and magnesium as bone density naturally decreases. B vitamins become more important for energy production and cognitive function. Antioxidant needs increase to combat age-related oxidative stress. Additionally, declining estrogen during perimenopause affects many body systems, creating unique nutritional demands.

Should I take a multivitamin or individual supplements?

A quality multivitamin designed for women over 40 provides a good foundation. However, some nutrients like vitamin D, omega-3s, and magnesium often require additional supplementation to reach optimal levels. Your specific needs depend on your diet, health conditions, medication use, and lifestyle factors. Consulting with a healthcare provider can help determine your best approach.

When will I notice results from taking vitamins?

Timeframes vary depending on the supplement and your body’s initial levels. Water-soluble vitamins like B complex may produce noticeable energy improvements within weeks. Fat-soluble vitamins like D can take 2-3 months to reach optimal levels. Supplements for skin, hair and nails typically require 3-6 months of consistent use before results become apparent.

Can vitamins interact with medications?

Yes. Several supplements can interact with common medications. For example, calcium can interfere with certain antibiotics, vitamin K can affect blood thinners, and St. John’s Wort interacts with many medications. Always inform your healthcare provider about all supplements you take to prevent potentially dangerous interactions.

Should I get my nutrient levels tested before supplementing?

Testing provides valuable information about your specific needs and helps prevent over-supplementation. Tests for vitamin D, iron, B12, and magnesium levels are particularly useful for women over 40. Work with a healthcare provider to determine which tests would be most beneficial based on your symptoms and health history.

Last update on 2025-05-13 / Affiliate links / Images from Amazon Product Advertising API Some of the links on this website are affiliate links, which means that at no additional cost to you, I earn a commission if you click through and make a purchase. I only recommend products and services that I believe will add value to my readers. Thank you for your support!